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Arizona Cardinals take on Seattle Seahawks at 8:15 PM ET on Thursday, September 25, 2025, at State Farm Stadium in Glendale, Arizona. This Week 4 NFL regular season game launches Thursday Night Football, pitting NFC West rivals with identical 2-1 records against each other. Seattle, quarterbacked by Sam Darnold, holds a 1.5-point edge in betting odds, while Arizona, led by Kyler Murray, aims to snap a seven-game losing streak against their divisional foe. Fans in the U.S. and Brazil can access live broadcasts through multiple TV and streaming platforms.

The game features Seattle’s elite defense, allowing just 18.3 points per game, against Arizona’s dynamic passing attack, impacted by the absence of running back James Conner. This matchup sets the stage for a critical Week 4 showdown.

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Live broadcast options

U.S. and Brazilian audiences have several ways to watch the game live.

  • Prime Video: Streams in the U.S. with English commentary, starting at 8:00 PM ET.
  • SporTV 2: Airs in Brazil at 9:15 PM Brasília time, with Portuguese narration.
  • DAZN: Offers NFL Game Pass globally, including replays and real-time stats.
  • Globoplay: Available in Brazil for sports package subscribers, compatible with mobile devices.

These platforms deliver HD quality and pre-game coverage for an immersive experience.

Stadium and team preparations

State Farm Stadium anticipates 63,000 fans under its retractable roof. The nighttime temperature is forecast at 82°F, ideal for football.

Arizona adapts without Conner, relying on Trey Benson, who projects 100 rushing yards. Murray has thrown for 682 yards this season.

Seattle leans on Kenneth Walker III, who rushed for 120 yards in Week 3. The Seahawks’ defense has forced five turnovers.

The synthetic turf favors quick passing plays, shaping both teams’ strategies.

Arizona’s offensive approach

Kyler Murray, with a 68% completion rate, targets tight end Trey McBride, who has 18 receptions and two touchdowns. Wideout Marvin Harrison Jr. adds speed, averaging 50 yards per game at home.

Arizona’s run game aims for 120 yards, split between Benson and Ezekiel Elliott. The offense scored 25 points in the first half across three games.

The Cardinals face a tough Seattle secondary, which has four interceptions this season.

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Seattle’s defensive strength

Mike Macdonald’s unit ranks among the NFL’s top five, conceding 18.3 points per game. Defensive lineman Leonard Williams has two sacks, focusing on disrupting Murray early.

Cornerback Josh Jobe’s recent interception bolsters Seattle’s backfield. The team excels at forcing turnovers, with five in three games.

Seattle limits opponents to 210 passing yards on average, challenging Arizona’s air attack.

Key players to watch

Several athletes could tilt the game’s outcome.

  • Kenneth Walker III: Scored in three road games against winning teams.
  • Trey McBride: Leads tight ends with 18 catches and two scores.
  • Josh Jobe: Notched a key interception in Week 3.
  • Jaxon Smith-Njigba: Seattle’s reliable receiver with sharp routes.
  • Derion Kendrick: Cornerback with two ball steals this season.

These players elevate the stakes of the rivalry.

Rivalry and stakes

Seattle has won the last seven matchups, averaging 28 points per game. Arizona’s last home victory over the Seahawks came in 2020.

A loss drops either team to 0-2 in the NFC West, with only a 9.6% playoff qualification rate for such teams since 2002.

The game’s first quarter typically sees under 14 points, per Thursday Night Football trends.

Maria Clara é colaboradora da redação do Mix Vale, portal de notícias com cobertura de Brasil e mundo. Produz conteúdo nas editorias de economia e benefícios, com foco em informação de serviço para o leitor brasileiro. Escreve para o portal desde 2016: Formação: Atriz.

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