Discover all the safe passwords in Resident Evil Requiem to secure the trophy

Players venturing through the dark corridors of Resident Evil: Requiem soon discover that survival at Rhodes Hill Care Center depends on scarce resources. To alleviate this tension, the developers spread several safes across the scene, requiring precise combinations of left (clockwise) and right (counterclockwise) turns. Uncovering all of these secret compartments rewards the user with the “No Vault Is Safe” achievement, one of the most popular challenges since the title’s launch in 2026. Understanding the exact location and codes saves valuable time during exploration.

The true value of these armored compartments lies in the Ancient Coins stored inside, which act as currency in the main lobby to upgrade equipment, such as the S&S M232 pistol. In addition to in-game money, players find crucial maps and heavy ammunition to face areas dominated by mutant creatures. It is worth noting that, when selecting the “Madhouse” difficulty, the passwords undergo drastic changes to confuse veterans, although the steel boxes remain in the same places as in the standard campaign.

• Bar and Lounge Area: yields three Ancient Coins.
• Medical Examination Room: holds three more Ancient Coins.
• Waiting Room: contains two Ancient Coins and starts unlocked.
• Fornalha Basement: hides Mr. Raccoon’s map and extra bullets.
• ARK Sterilization Chamber: provides a medical injector, ammunition and Molotov cocktail.
• ARK Monitor Control: Offers another injector, corrosive acid, and an empty bottle.

First secret compartment located in the Bar and Lounge

In the opening hours of the campaign, upon reaching the second floor of the Rhodes Hill Care Center, the protagonist comes across the first safe. The environment is often infested with basic enemies, requiring tactical clearing before attempting to safely enter the password. The document found nearby reveals the correct sequence: turn the knob left to 10, then right to 80, and finally left to 30 to hear the unlocking click.

The prize for solving this initial puzzle is three Ancient Coins, which are essential for starting the improvement tree in the safe lobby. Interestingly, the S&S M232 pistol can be collected from a nearby table, allowing the player to invest these newly acquired resources to increase the base weapon’s firepower immediately.

How to access locked resources in the Exam Room

Accessible through the east lobby, the Exam Room houses the second safe, discreetly positioned in the right corner of the medical room. To open this box, the survivor must follow the notes in a medical record left on the adjacent table, which indicates the combination: right on 30, left on 10 and right on 50.

Upon opening the metal door, three more Ancient Coins are added to the inventory, totaling six coins if the player has explored the previous hall. This exact amount allows you to purchase the first major upgrade in ammo capacity or raw damage, making subsequent confrontations immensely easier.

The narrative surprise of the safe in the Waiting Room

Behind the Waiting Room reception desk, fans of the franchise find an atypical situation by the standards of the horror series. The safe in this sector already has the door wide open, allowing anyone to simply reach out and pick up the two Ancient Coins left inside, without the need to look for documents with passwords.

This detail serves as environmental narrative, suggesting that another survivor or hospital employee hastily ransacked the place before the protagonist’s arrival. It’s a welcome relief that contributes to achievement progression without requiring additional mental effort during the escape.

The secret hidden in the depths of Porão da Fornalha

The journey through the bowels of the building leads to the Furnace Basement, where you need to use a two-prong plug to restore power to the forklift room. The safe in this obscure area requires the combination right 60, left 40 and right 80, revealing an extremely important item for trophy hunters: the detailed map with the location of all Mr. Raccoon figurines.

Along with the cartographic document, the player receives ten pistol bullets, a vital resource for dealing with the abominations that patrol the underground corridors. The figurines marked on the map are part of an extensive side quest, and missing this guide can force an entire replay just to find the forgotten collectibles.

Advanced challenges in the ARK complex laboratories

The final stretch of the game takes the action to the ARK research complex, a highly dangerous zone infested by Lickers and other experimental biological weapons. The codes needed to survive this sector are documented in the Biological Weapons Repository 05 archive, and the supplies stored here are the only way to mitigate the steep difficulty curve of the last few hours of the campaign.

Exploring the Sterilization Room and Monitor Control center requires extreme caution, as the noise attracts lethal creatures in a matter of seconds. Incendiary items, like the Molotov cocktails found in these safes, become mandatory tools for crowd control when enemies corner the character.

Exact match for Sterilization Chamber

To unlock the compartment located on the lower level of the ARK Sterilization Chamber, turn the disc to the right at 10, left at 90 and right at 20. The execution must be quick, as Lickers often invade the perimeter, forcing the player to adopt stealthy tactics or enter into direct combat immediately after collecting the medical injector, the 15 bullets and the molotov.

This survival pack is strategically placed to ensure the protagonist has enough resources to make the perilous journey back to the main lobby. Without this injection of supplies, many players end up dying repeatedly due to lack of ammunition or healing items at this critical stage in the story.

Chemical supplies in the Monitor Control room

Located near the lobby that displays a large decorative sphere, the Monitor Control vault holds the laboratory’s latest secrets. Entering the sequence left 50, right 60, and left 80 rewards the effort with an additional medical injector, a vial of highly corrosive acid, and an empty item crafting bottle.

The real use of this loot is the ability to combine the acid with the glass bottle to craft a devastating improvised grenade. This chemical explosive not only melts the armor of elite enemies, but also serves to unclog sealed doors that block progress within ARK facilities.

Drastic password changes on Madhouse difficulty

When starting a campaign in the relentless Madhouse mode, players’ muscle memory is put to the test as vault locations are retained but passwords completely change. The Bar compartment now requires the sequence right 20, left 50 and right 30, while the Exam Room only opens with left 50, right 30 and left 90.

The basement safe is reconfigured to left 70, right 50 and left 20, and the sterilization area changes to left 80, right 50 and left 0. In the control room, the new code is right 20, left 0 and right 70, with the added bonus that the previously friendly Waiting Room is now completely empty, with no free coins.

This change in mechanics was specifically designed to punish anyone who tries to use normal difficulty guides, requiring a new thorough exploration of the scenario. Conquering all the secrets on this difficulty is a requirement to platinum the game, considerably increasing the title’s replayability factor.

The impact of Ancient Coins on the game economy

The economy system based on ancient artifacts allows the player to purchase permanent improvements to the Rhodes Hill Center cages. Accumulating six coins in the first areas allows you to double