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The kidneys perform vital functions discreetly, constantly acting to balance the body. They filter the blood, remove impurities, control blood pressure, assist in hormone production and adjust the balance of fluids and minerals. However, despite its relevance, chronic kidney disease often progresses without showing noticeable signs in its early stages.

It is estimated that approximately 10% of adults live with some level of chronic kidney disease. The great difficulty lies in the fact that most of these people are unaware of the diagnosis, as the condition can evolve without clear symptoms for a long period. When the first signs appear, it is common that a considerable portion of the renal capacity is already compromised, reducing the opportunities to slow or reverse its progress.

In this context, the two main triggers for this clinical condition continue to be diabetes and high blood pressure. However, in recent years, obesity has emerged as a factor of increasing concern. Although it still does not have the same influence as the two primary causes, excess weight significantly increases the risk of damage to the kidneys, both by promoting the emergence of diabetes and hypertension and by inducing changes that directly affect the functional capacity of these organs.

How diabetes became the leading cause of chronic kidney disease

Diabetes remains the most common reason for chronic kidney disease in many global regions. High blood sugar constantly damages the tiny blood vessels in the kidneys, gradually and persistently reducing their ability to purify the blood.

Since this progression occurs asymptomatically, the first signs are usually identified through laboratory tests. An initial indication is the detection of small amounts of albumin in the urine, a protein that is normally maintained in the kidneys and whose excretion may point to early kidney damage.

As the condition progresses, changes appear in blood tests, such as an increase in creatinine levels and a decrease in the glomerular filtration rate. Without regular doctor visits, these changes risk going unnoticed.

Therefore, it is essential that all people diagnosed with diabetes frequently monitor their kidney health, even in the absence of symptoms.

Understand the two-way link between hypertension and kidney damage

High blood pressure is another major contributor to chronic kidney disease. High blood pressure repeatedly attacks the kidneys’ blood vessels, progressively decreasing their ability to filter blood over time.

However, this connection operates in a two-way street. As the kidneys lose their functionality, they also contribute to increased blood pressure. Thus, a harmful cycle is established: hypertension worsens kidney damage, and affected kidneys increasingly complicate the maintenance of controlled blood pressure.

This dynamic explains why so many individuals develop difficult-to-manage hypertension when kidney disease is already at an advanced stage. Keeping blood pressure within recommended limits is one of the most efficient strategies for slowing the progression of the condition and simultaneously reducing the risk of cardiovascular problems.

Obesity drives kidney problems and their consequences

For a long time, obesity was perceived only as an indirect risk for kidney disease, as it increased the chances of developing diabetes and hypertension.

We now recognize that it can also directly affect kidney health. Overweight increases the renal workload, stimulates inflammatory processes and induces changes in the structure that accelerate the decline in kidney function. Although it is not classified as a cause as impactful as diabetes and hypertension, obesity functions as a relevant complementary factor, intensifying the danger of chronic kidney disease.

The increase in obesity in children, young people and adults generates concern, as it anticipates the emergence of kidney problems. The earlier the loss of kidney function occurs, the longer the exposure to the risk of kidney failure and cardiovascular complications throughout life.

Prevention remains the most effective approach.

In addition to changes in daily habits, advances in the treatment of diabetes, hypertension and kidney disease itself have considerably expanded the chances of protecting kidney function. With an early diagnosis, medications are available that can delay the progression of the disease and reduce the need for dialysis.

Controlling blood sugar and blood pressure, maintaining an adequate weight, practicing physical exercise consistently, having a balanced diet and taking preventive exams are actions proven to be effective in protecting the kidneys.

Chronic kidney disease often progresses without obvious signs, however, its main risk factors are recognized and, to a large extent, controllable. Managing diabetes, keeping blood pressure regulated and preventing overweight are crucial steps that help maintain kidney function and can prevent countless people from needing dialysis or kidney transplants. In the area of ​​nephrology, prevention and early diagnosis remain the most valuable instruments to ensure lasting well-being and health.

Luís Henrique Costa é jornalista formado pela FMU, editor-chefe e fundador do Mix Vale, portal de notícias em atividade desde 2013. Responde pela direção editorial do veículo, que cobre Brasil e mundo em economia, benefícios sociais, esportes, tecnologia, ciência e entretenimento. Atua na área há mais de 15 anos e lidera uma equipe de cerca de 15 colaboradores.

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